Randomised, Controlled, Assessor Blind Trial Comparing 4% Dimeticone Lotion with 0.5% Malathion Liquid for Head Louse Infestation

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Randomised, Controlled, Assessor Blind Trial Comparing 4% Dimeticone Lotion with 0.5% Malathion Liquid for Head Louse Infestation

BACKGROUND Malathion 0.5% has been the most prescribed pediculicide in the United Kingdom for around 10 years, and is widely used in Europe and North America. Anecdotal reports suggest malathion treatments are less effective than formerly, but this has not been confirmed clinically. This study was designed to determine whether malathion is still effective and if 4% dimeticone lotion is a more e...

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Treatment of head louse infestation with 4% dimeticone lotion: randomised controlled equivalence trial.

OBJECTIVE To evaluate the efficacy and safety of 4% dimeticone lotion for treatment of head louse infestation. DESIGN Randomised controlled equivalence trial. SETTING Community, with home visits. PARTICIPANTS 214 young people aged 4 to 18 years and 39 adults with active head louse infestation. INTERVENTIONS Two applications seven days apart of either 4.0% dimeticone lotion, applied for ...

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Primary care Treatment of head louse infestation with 4% dimeticone lotion: randomised controlled equivalence trial

Objective To evaluate the efficacy and safety of 4% dimeticone lotion for treatment of head louse infestation. Design Randomised controlled equivalence trial. Setting Community, with home visits. Participants 214 young people aged 4 to 18 years and 39 adults with active head louse infestation. Interventions Two applications seven days apart of either 4.0% dimeticone lotion, applied for eight ho...

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Neem-silicone lotion and ultrasound nit comb: a randomised, controlled clinical trial treating head louse infestation

Background: A neem-based conditioner lotion (ONC) used against head lice was previously tested clinically and shown to be relatively ineffective. To improve the activity against lice and their eggs, it was reformulated into a silicone vehicle (NNC) as part of a project to improve pediculicidal medical devices. An ultrasound nit comb was also developed to be used in conjunction with the neem lot...

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Comparison of phenothrin mousse, phenothrin lotion, and wet-combing for treatment of head louse infestation in the UK: a pragmatic randomised, controlled, assessor blind trial

In this investigation of effectiveness of an alternative pediculicide dosage form, we recruited 228 children and 50 adult participants from Bedfordshire, UK, to a randomised, controlled, assessor blind trial comparing two insecticide products with mechanical removal of lice as a control group.  Participants using insecticide were treated with either the investigative 0.5% phenothrin mousse, for...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2007

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0001127